Structure elucidation and biosynthesis of lysine-rich cyclic peptides in Xenorhabdus nematophila.

Authors :: Fuchs SW
Proschak A
Jaskolla TW
Karas M
Bode HB
Source :: Organic & biomolecular chemistry [Org Biomol Chem] 2011 May 07; Vol. 9 (9), pp. 3130-2. Date of Electronic Publication: 2011 Mar 21.
Publication Year :: 2011
Abstract: Thirteen novel PAX (peptide-antimicrobial-Xenorhabdus) peptides were identified in Xenorhabdus nematophila HGB081. Their structures including the absolute configuration were elucidated using a combination of labeling experiments, detailed MS/MS experiments, the advanced Marfey's method, and a detailed analysis of the biosynthesis gene cluster, which was identified as well.

Subjects :: Lysine chemistry
Molecular Structure
Peptides, Cyclic biosynthesis
Xenorhabdus metabolism
Peptides, Cyclic chemistry
Xenorhabdus chemistry

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