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Florid, papillary endosalpingiosis of the axillary lymph nodes.
- Source :
-
The breast journal [Breast J] 2011 May-Jun; Vol. 17 (3), pp. 268-72. Date of Electronic Publication: 2011 Apr 08. - Publication Year :
- 2011
-
Abstract
- A 55-year-old woman underwent radical mastectomy and axillary node dissection because of an invasive ductal carcinoma with neuroendocrine features. Histologically, all 22 sampled lymph nodes had widespread cystic inclusions lined by a regular, serous-type epithelium positive for cytokeratin-7, WT-1, CA125, and estrogen receptors. Papillary projections were found in the lumen of some cysts. The lesions were consistent with florid, papillary endosalpingiosis (FPE), a hitherto unreported condition in a supradiaphragmatic location. Metastases from papillary carcinomas of ovary, breast, or thyroid were excluded considering the lesion's immunophenotype (negative for mammaglobin and TTF-1) and the absence of both atypical features and a concurrent abdominal serous tumor. In only one node, lesions co-existed with a metastasis of breast carcinoma. Supradiaphragmatic FPE represents a pitfall in the differential diagnosis of metastases, especially in sentinel nodes, since it may increase their size and reveal an unusual ultrasonographic image. Clinicopathologic findings and a focused immunohistochemical study led to the correct diagnosis of this benign lesion.<br /> (© 2011 Wiley Periodicals, Inc.)
- Subjects :
- Axilla
Breast Neoplasms complications
Breast Neoplasms metabolism
Carcinoma, Ductal, Breast complications
Carcinoma, Ductal, Breast metabolism
Diagnosis, Differential
Female
Humans
Lymphatic Diseases complications
Lymphatic Diseases metabolism
Middle Aged
Sentinel Lymph Node Biopsy
Breast Neoplasms pathology
Carcinoma, Ductal, Breast pathology
Lymph Nodes pathology
Lymphatic Diseases pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1524-4741
- Volume :
- 17
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The breast journal
- Publication Type :
- Academic Journal
- Accession number :
- 21477174
- Full Text :
- https://doi.org/10.1111/j.1524-4741.2011.01081.x