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A stereoselective oxidative polycyclization process mediated by a hypervalent iodine reagent.
- Source :
-
Organic letters [Org Lett] 2011 Jul 01; Vol. 13 (13), pp. 3406-9. Date of Electronic Publication: 2011 May 27. - Publication Year :
- 2011
-
Abstract
- Activation of phenol derivatives with a hypervalent iodine reagent promotes the formation of bicyclic and tricyclic products via a cationic cyclization process. The method allows efficient one-step syntheses of scaffolds present in several natural products and occurs with total stereocontrol, governed by 1,3 allylic strain interactions and by the configuration of the side chain double bonds.
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 13
- Issue :
- 13
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 21619047
- Full Text :
- https://doi.org/10.1021/ol201149u