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[The effect of protein metabolism and immunologic function of glutamine after operation in elder gastrointestinal tumor].
- Source :
-
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology [Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi] 2011 Mar; Vol. 27 (3), pp. 322-3. - Publication Year :
- 2011
-
Abstract
- Aim: To explore the effect of protein metabolism and immunologic function of glutamine after operation in elder gastrointestinal tumor.<br />Methods: Form march 2007 to 2010, 87 cases of elder gastrointestinal tumor were given parenteral nutrition and glutamine 0.6 g/( Kg x d).The period of treatment were 8 days. IgA, IgG, IgM were CD4, measured by single immunodiffusion, CD3(+), CD4(+), CD8(+), CD4(+) /CD8(+) were measured by immunohistochemical method, and the index(Alb, PAB, TF, nitrogen equilibrium) were monitored the proteid catabolism distribution.<br />Results: After the treatment, CD3(+), CD4(+), CD8(+), CD4(+)/CD8(+), IgG, IgA, IgM were evidently declined( P <0.05). Alb, PAB, TF were evidently declined in 4 days postoperatively (P < 0.05), the restore were more obvious in 8 days postoperatively (P < 0. 05). Nitrogen equilibrium was worse in the early postoperative and the restore were more obvious in 8 days postoperatively (P < 0.05).<br />Conclusion: Glutamine can improve patient's nutrition, enhance their immunologic function.
- Subjects :
- Aged
CD4-CD8 Ratio
CD8-Positive T-Lymphocytes metabolism
Chemotherapy, Adjuvant
Female
Gastrointestinal Neoplasms immunology
Humans
Lymphocyte Count
Male
Middle Aged
Parenteral Nutrition
Postoperative Period
Serum Albumin metabolism
CD4-Positive T-Lymphocytes metabolism
Gastrointestinal Neoplasms drug therapy
Gastrointestinal Neoplasms surgery
Glutamine administration & dosage
Immunoglobulin A metabolism
Immunoglobulin G metabolism
Immunoglobulin M metabolism
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1007-8738
- Volume :
- 27
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
- Publication Type :
- Academic Journal
- Accession number :
- 21638931