High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: a prospective cohort study.

Authors :: Kavsak PA
Walsh M
Srinathan S
Thorlacius L
Buse GL
Botto F
Pettit S
McQueen MJ
Hill SA
Thomas S
Mrkobrada M
Alonso-Coello P
Berwanger O
Biccard BM
Cembrowski G
Chan MT
Chow CK
de Miguel A
Garcia M
Graham MM
Jacka MJ
Kueh JH
Li SC
Lit LC
Martínez-Brú C
Naidoo P
Nagele P
Pearse RM
Rodseth RN
Sessler DI
Sigamani A
Szczeklik W
Tiboni M
Villar JC
Wang CY
Xavier D
Devereaux PJ
Source :: Clinical biochemistry [Clin Biochem] 2011 Aug; Vol. 44 (12), pp. 1021-4. Date of Electronic Publication: 2011 May 24.
Publication Year :: 2011
Abstract: Objectives: To determine the proportion of noncardiac surgery patients exceeding the published 99th percentile or change criteria with the high sensitivity Troponin T (hs-TnT) assay.<br />Design and Methods: We measured hs-TnT preoperatively and postoperatively on days 1, 2 and 3 in 325 adults.<br />Results: Postoperatively 45% (95% CI: 39-50%) of patients had hs-TnT≥14ng/L and 22% (95% CI:17-26%) had an elevation (≥14ng/L) and change (>85%) in hs-TnT.<br />Conclusion: Further research is needed to inform the optimal hs-TnT threshold and change in this setting.<br /> (Copyright © 2011 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.)

Subjects :: Aged
Cohort Studies
Female
Humans
Male
Middle Aged
Surgical Procedures, Operative
Postoperative Period
Preoperative Period
Troponin T blood

Full Text Access

Tools