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Homologous recombination research is heating up and ready for therapy.
- Source :
-
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2011 Jun 14; Vol. 108 (24), pp. 9731-2. Date of Electronic Publication: 2011 Jun 03. - Publication Year :
- 2011
- Subjects :
- Animals
BRCA2 Protein genetics
Benzoquinones pharmacology
Cell Line, Tumor
DNA Repair
DNA-Binding Proteins genetics
DNA-Binding Proteins metabolism
Humans
Immunoblotting
Lactams, Macrocyclic pharmacology
Mice
Neoplasms, Experimental genetics
Neoplasms, Experimental metabolism
Neoplasms, Experimental pathology
Phthalazines pharmacology
Piperazines pharmacology
Poly(ADP-ribose) Polymerase Inhibitors
Poly(ADP-ribose) Polymerases genetics
Quinazolines pharmacology
RNA Interference
Rats
Recombination, Genetic drug effects
Recombination, Genetic radiation effects
Transplantation, Heterologous
Tumor Burden drug effects
Tumor Burden radiation effects
BRCA2 Protein metabolism
Hot Temperature
Poly(ADP-ribose) Polymerases metabolism
Recombination, Genetic genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1091-6490
- Volume :
- 108
- Issue :
- 24
- Database :
- MEDLINE
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Academic Journal
- Accession number :
- 21642535
- Full Text :
- https://doi.org/10.1073/pnas.1106456108