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The economic burden of Clostridium difficile.
- Source :
-
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2012 Mar; Vol. 18 (3), pp. 282-9. Date of Electronic Publication: 2011 Jun 10. - Publication Year :
- 2012
-
Abstract
- Although Clostridium difficile (C. difficile) is the leading cause of infectious diarrhoea in hospitalized patients, the economic burden of this major nosocomial pathogen for hospitals, third-party payers and society remains unclear. We developed an economic computer simulation model to determine the costs attributable to healthcare-acquired C. difficile infection (CDI) from the hospital, third-party payer and societal perspectives. Sensitivity analyses explored the effects of varying the cost of hospitalization, C. difficile-attributable length of stay, and the probability of initial and secondary recurrences. The median cost of a case ranged from $9179 to $11 456 from the hospital perspective, $8932 to $11 679 from the third-party payor perspective, and $13 310 to $16 464 from the societal perspective. Most of the costs incurred were accrued during a patient's primary CDI episode. Hospitals with an incidence of 4.1 CDI cases per 100 000 discharges would incur costs ≥$3.2 million (hospital perspective); an incidence of 10.5 would lead to costs ≥$30.6 million. Our model suggests that the annual US economic burden of CDI would be ≥$496 million (hospital perspective), ≥$547 million (third-party payer perspective) and ≥$796 million (societal perspective). Our results show that C. difficile infection is indeed costly, not only to third-party payers and the hospital, but to society as well. These results are consistent with current literature citing C. difficile as a costly disease.<br /> (© 2011 The Authors. Clinical Microbiology and Infection © 2011 European Society of Clinical Microbiology and Infectious Diseases.)
- Subjects :
- Aged
Aged, 80 and over
Clostridium Infections microbiology
Computer Simulation
Cross Infection microbiology
Diarrhea economics
Diarrhea epidemiology
Diarrhea microbiology
Humans
Incidence
Models, Statistical
United States epidemiology
Clostridioides difficile isolation & purification
Clostridium Infections economics
Clostridium Infections epidemiology
Cross Infection economics
Cross Infection epidemiology
Health Care Costs statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 1469-0691
- Volume :
- 18
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 21668576
- Full Text :
- https://doi.org/10.1111/j.1469-0691.2011.03571.x