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Selective arterial stimulation of secretin in localization of gastrinomas.
- Source :
-
Surgery, gynecology & obstetrics [Surg Gynecol Obstet] 1990 Sep; Vol. 171 (3), pp. 196-200. - Publication Year :
- 1990
-
Abstract
- In two patients with malignant gastrinoma and the Zollinger-Ellison syndrome, we were able to use selective arterial stimulation with secretin as a technique to localize the lesions accurately, allowing resection. The technique of selected arterial secretin stimulation is one of measuring variations in gastrin levels in both the hepatic vein and a peripheral artery at specified times after injection of secretin into a specific artery. When the criteria for localization have been met, one can plot the presence of the gastrinoma within the blood supply of the injected artery and, using angiograms, thus accurately localize the lesion. This method promises to be a valuable additional tumor-localizing procedure, particularly when gastrinomas are extrapancreatic.
- Subjects :
- Adenoma, Islet Cell blood
Adenoma, Islet Cell pathology
Adenoma, Islet Cell surgery
Angiography
Drug Evaluation
Female
Gastrinoma blood
Gastrinoma pathology
Gastrinoma surgery
Gastrins blood
Hepatic Veins
Humans
Middle Aged
Pancreatectomy
Pancreatic Neoplasms blood
Pancreatic Neoplasms pathology
Pancreatic Neoplasms surgery
Time Factors
Zollinger-Ellison Syndrome blood
Zollinger-Ellison Syndrome diagnostic imaging
Zollinger-Ellison Syndrome pathology
Zollinger-Ellison Syndrome surgery
Adenoma, Islet Cell diagnosis
Gastrinoma diagnosis
Pancreatic Neoplasms diagnosis
Secretin
Subjects
Details
- Language :
- English
- ISSN :
- 0039-6087
- Volume :
- 171
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Surgery, gynecology & obstetrics
- Publication Type :
- Academic Journal
- Accession number :
- 2166970