The newer fluoroquinolones.

Authors :: Bolon MK
Source :: The Medical clinics of North America [Med Clin North Am] 2011 Jul; Vol. 95 (4), pp. 793-817, viii.
Publication Year :: 2011
Abstract: Clinicians have enthusiastically used fluoroquinolones owing to their good safety profile and wide range of indications. This article reviews fluoroquinolone pharmacology, pharmacodynamic principles, and fluoroquinolone resistance mechanisms, highlighting recent trends in the epidemiology of fluoroquinolone resistance among gram-negative organisms and Streptococcus pneumonia. Important fluoroquinolone safety concerns are discussed, along with indications for the most commonly used fluoroquinolones--ciprofloxacin, levofloxacin, and moxifloxacin.<br /> (Copyright © 2011 Elsevier Inc. All rights reserved.)