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Dietary intake of fruit and vegetables and risk of non-Hodgkin lymphoma.
- Source :
-
Cancer causes & control : CCC [Cancer Causes Control] 2011 Aug; Vol. 22 (8), pp. 1183-95. Date of Electronic Publication: 2011 Jun 22. - Publication Year :
- 2011
-
Abstract
- Objective: Few studies have evaluated the potential association between consumption of fruit and vegetables and non-Hodgkin lymphoma (NHL) by histologic subtype, and the results of these studies have been inconsistent.<br />Methods: A detailed history of dietary practices and food preferences was collected using a food frequency questionnaire from 348 cases and 470 controls in a population-based, case-control study conducted in Nebraska during 1999-2002. Risk for the highest versus lowest quartile or tertile of intake was estimated by odds ratios (ORs) and 95% confidence interval (CIs).<br />Results: A lower risk of overall NHL was associated with a high intake of green leafy vegetables (OR = 0.6; CI = 0.3-1.0) and cruciferous vegetables (OR = 0.7; CI = 0.4-1.0). Analysis by subtype showed that green leafy vegetable intake was associated with a lower risk of follicular lymphoma (OR = 0.5; CI = 0.3-0.8) and diffuse large B-cell lymphoma (DLBCL) (OR = 0.5; CI = 0.3-0.9), while consumption of cruciferous vegetables was associated with a lower risk of DLBCL (OR = 0.4; CI = 0.2-0.8). No association was found with intake of total vegetables, carotene-rich vegetables, or all fruit. For nutrients, the risk of NHL overall was inversely associated with a higher intake of β-cryptoxanthin (OR = 0.6; CI = 0.4-0.9), magnesium (OR = 0.4; CI = 0.2-0.6), potassium (OR = 0.5; CI = 0.3-1.0), and fiber (OR = 0.6; CI = 0.3-1.0), but positively associated with a higher intake of retinol (OR = 1.7; CI = 1.1-2.8). Intakes of vitamin E, magnesium, and potassium were inversely associated with the risk of DLBCL.<br />Conclusion: A higher intake of green leafy vegetables and cruciferous vegetables is associated with a lower risk of NHL overall, particularly follicular lymphoma and DLBCL.
Details
- Language :
- English
- ISSN :
- 1573-7225
- Volume :
- 22
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Cancer causes & control : CCC
- Publication Type :
- Academic Journal
- Accession number :
- 21695384
- Full Text :
- https://doi.org/10.1007/s10552-011-9797-5