Back to Search
Start Over
Urinary tract infection associated with conditions causing urinary tract obstruction and stasis, excluding urolithiasis and neuropathic bladder.
- Source :
-
World journal of urology [World J Urol] 2012 Feb; Vol. 30 (1), pp. 77-83. Date of Electronic Publication: 2011 Jul 01. - Publication Year :
- 2012
-
Abstract
- Purpose: The aim of this study was to examine urinary tract infection (UTI) associated with conditions causing urinary tract obstruction and stasis, excluding urolithiasis and neuropathic bladder dysfunction.<br />Methods: An electronic literature search was performed using the key words urinary tract infection (UTI), benign prostatic hyperplasia (BPH), hydronephrosis, obstruction, reflux, diverticulum, urethra, and stricture. In total, 520 abstracts were reviewed, 210 articles were studied in detail, and 36 were included as references.<br />Results: It is one of the axioms of Urological practice that urinary tract obstruction and stasis predispose to UTI. Experimental studies indicate that, whereas transurethral inoculates of bacteria are rapidly eliminated from the normal bladder, urethral obstruction leads to cystitis, pyelonephritis, and bacteremia. BPH is, next to urolithiasis, the most common cause of urinary tract obstruction predisposing to UTI. Urethral stricture remains a common cause of UTI in many parts of the world. Urinary stasis in diverticula of the urethra or bladder predisposes to UTI. Experimental studies have shown that, whereas the normal kidney is relatively resistant to infection by organisms injected intravenously, ureteric obstruction predisposes to pyelonephritis. It also causes renal dysfunction which impairs the excretion of antibiotics in the urine, making eradication of bacteria difficult.<br />Conclusions: In patients with UTI and urinary tract obstruction, targeted antibiotic treatment according to urine culture should be complemented with urgent drainage (bladder catheterization, percutaneous nephrostomy or ureteric stenting) followed by definitive surgery to remove the cause of obstruction or stasis once infection is under control.
- Subjects :
- Female
Humans
Hydronephrosis complications
Male
Prostatic Hyperplasia complications
Prostatic Neoplasms complications
Ureteral Obstruction complications
Urethral Stricture complications
Urinary Tract Infections drug therapy
Diverticulum complications
Urinary Bladder Diseases complications
Urinary Tract Infections complications
Urologic Diseases complications
Subjects
Details
- Language :
- English
- ISSN :
- 1433-8726
- Volume :
- 30
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- World journal of urology
- Publication Type :
- Academic Journal
- Accession number :
- 21720861
- Full Text :
- https://doi.org/10.1007/s00345-011-0725-9