Evidence of impaired endometrial receptivity after ovarian stimulation for in vitro fertilization: a prospective randomized trial comparing fresh and frozen-thawed embryo transfers in high responders.

Authors :: Shapiro BS
Daneshmand ST
Garner FC
Aguirre M
Hudson C
Thomas S
Source :: Fertility and sterility [Fertil Steril] 2011 Aug; Vol. 96 (2), pp. 516-8. Date of Electronic Publication: 2011 Jul 06.
Publication Year :: 2011
Abstract: Clinical pregnancy rates of 80% and 65% were observed in cycles using thawed and fresh embryos, respectively, although embryo quality indicators revealed morphologically and numerically inferior embryo cohorts after cryopreservation. Subsequent logistic regression analysis controlled for differences in embryo quality and revealed significantly greater probability of clinical pregnancy with thawed embryos when compared with fresh, suggesting a negative effect of ovarian stimulation on endometrial receptivity.<br /> (Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.)

Subjects :: Adult
Female
Humans
Infertility physiopathology
Logistic Models
Nevada
Pregnancy
Pregnancy Rate
Prospective Studies
Treatment Outcome
Blastocyst
Cryopreservation
Embryo Implantation
Embryo Transfer adverse effects
Endometrium physiopathology
Fertilization in Vitro adverse effects
Infertility therapy
Ovulation Induction adverse effects

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