Ag K-edge EXAFS analysis of DNA-templated fluorescent silver nanoclusters: insight into the structural origins of emission tuning by DNA sequence variations.

Authors :: Neidig ML
Sharma J
Yeh HC
Martinez JS
Conradson SD
Shreve AP
Source :: Journal of the American Chemical Society [J Am Chem Soc] 2011 Aug 10; Vol. 133 (31), pp. 11837-9. Date of Electronic Publication: 2011 Jul 19.
Publication Year :: 2011
Abstract: DNA-templated silver nanoclusters are promising biological fluorescence probes due to their useful fluorescence properties, including tunability of emission wavelength through DNA template sequence variations. Ag K-edge EXAFS analysis of DNA-templated silver nanoclusters has been used to obtain insight into silver nanocluster bonding, size, and structural correlations to fluorescence. The results indicate the presence of small silver nanoclusters (<30 silver atoms) containing Ag-Ag bonds and Ag-N/O ligations to DNA. The DNA sequence used leads to differences in silver-DNA ligation as well as silver nanocluster size. The results support a model in which cooperative effects of both Ag-DNA ligation and variations in cluster size lead to the tuning of the fluorescence emission of DNA-templated silver nanoclusters.<br /> (© 2011 American Chemical Society)

Subjects :: Base Sequence
Molecular Structure
X-Ray Absorption Spectroscopy
DNA chemistry
Fluorescence
Metal Nanoparticles chemistry
Silver chemistry

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