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Intravenous administration of magnesium and potassium solution lowers energy levels and increases success rates electrically cardioverting atrial fibrillation.
- Source :
-
Journal of cardiovascular electrophysiology [J Cardiovasc Electrophysiol] 2012 Jan; Vol. 23 (1), pp. 54-9. Date of Electronic Publication: 2011 Aug 04. - Publication Year :
- 2012
-
Abstract
- Background: External biphasic electrical cardioversion (CV) is a standard treatment option for patients suffering from acute symptoms of atrial fibrillation (AF). Nevertheless, CV is not always successful, and thus strategies to increase the success rate are desirable.<br />Objective: The purpose of this study was to evaluate the effect of intravenously administered K/Mg solution on the biphasic CV energy threshold and success rate to restore sinus rhythm (SR) in patients with AF.<br />Methods: The study consisted of 170 patients with persistent AF. The patients were randomly assigned to undergo biphasic CV either with (n = 84) or without (n = 86) pretreatment with K/Mg solution. An energy step-up protocol of 75, 100, and 150 W (J) was used.<br />Results: Biphasic CV of AF was effective in 81 (96.4%) patients in the pretreatment and 74 (86.0%) patients in the control group (P = 0.005). The effective energy level required to achieve SR was significantly lower in the pretreated group (140.8 ± 26.9 J vs 182.5 ± 52.2 J, P = 0.02). No K/Mg-solution-associated side effects such as hypotension or bradycardia were observed.<br />Conclusion: Administration of K/Mg solution positively influences the success rate of CV in patients with persistent AF. Furthermore, significantly less energy is required to successfully restore SR and therefore K/Mg pretreatment may facilitate SR restoration in patients undergoing CV for AF.<br /> (© 2011 Wiley Periodicals, Inc.)
- Subjects :
- Aged
Atrial Fibrillation diagnosis
Atrial Fibrillation physiopathology
Combined Modality Therapy
Electric Countershock adverse effects
Female
Germany
Humans
Infusions, Intravenous
Magnesium adverse effects
Male
Middle Aged
Potassium adverse effects
Treatment Outcome
Atrial Fibrillation therapy
Defibrillators
Electric Countershock instrumentation
Magnesium administration & dosage
Potassium administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1540-8167
- Volume :
- 23
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of cardiovascular electrophysiology
- Publication Type :
- Academic Journal
- Accession number :
- 21815963
- Full Text :
- https://doi.org/10.1111/j.1540-8167.2011.02146.x