Regulatory T cells in transplantation.

Authors :: Wood KJ
Source :: Transplantation proceedings [Transplant Proc] 2011 Jul-Aug; Vol. 43 (6), pp. 2135-6.
Publication Year :: 2011
Abstract: T Regulatory cells (Treg) play an important role in the induction and maintenance of immunological tolerance to self and alloantigens. Recent findings in experimental transplant models have demonstrated that Treg can control acute and delayed allograft rejection. Preclinical attempts to use Treg as a cellular therapy have been successfully undertaken demonstrating the safety and feasibility of such treatment, suggesting that they have therapeutic potential.<br /> (Copyright © 2011 Elsevier Inc. All rights reserved.)