Magnetic resonance spectroscopy of the canine brain at 3.0 T and 7.0 T.

Authors :: Martin-Vaquero P
da Costa RC
Echandi RL
Sammet CL
Knopp MV
Sammet S
Source :: Research in veterinary science [Res Vet Sci] 2012 Aug; Vol. 93 (1), pp. 427-9. Date of Electronic Publication: 2011 Aug 23.
Publication Year :: 2012
Abstract: The purpose of this study was to evaluate the feasibility of proton magnetic resonance spectroscopy (1H MRS) to study the concentration of metabolites in the brain of dogs at 3.0 and 7.0 T. Four healthy male beagles were scanned using 3.0 T and 7.0 T human magnetic resonance imaging (MRI) units. The results obtained showed that all dogs had excellent quality spectra for a small (1 cm3) and large (8 cm3) voxel at 3.0 T, whereas only 2 dogs had high quality spectra at 7.0 T due to insufficient water suppression. 1H MRS at 3.0 T appears to be a reliable method to study metabolite concentrations in the canine brain. The development of more advanced water suppression techniques is necessary to improve the results at 7.0 T.<br /> (Copyright © 2011 Elsevier Ltd. All rights reserved.)