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Evaluation of morbidity and mortality after anastomotic leakage following elective colorectal surgery in patients treated with or without mechanical bowel preparation.
- Source :
-
American journal of surgery [Am J Surg] 2011 Sep; Vol. 202 (3), pp. 321-4. - Publication Year :
- 2011
-
Abstract
- Background: A previous multicenter randomized trial demonstrated that mechanical bowel preparation (MBP) does not guard against anastomotic leakage in elective colorectal surgery. The aim of this complementary study was to evaluate the effects of MBP on morbidity and mortality after anastomotic leakage in elective colorectal surgery.<br />Methods: A subgroup analysis was performed of a randomized trial comparing the incidence of anastomotic leakage and septic complications with and without MBP in patients undergoing elective colorectal surgery.<br />Results: Elective colorectal surgery was performed in 1,433 patients with primary anastomoses, of whom 63 patients developed anastomotic leakage. Twenty-eight patients (44%) received MBP and 35 patients (56%) did not. Mortality rate, initial need for surgical reintervention, and extent of bowel contamination did not differ between groups (29% vs 40%; P = .497, P = .667, and P = .998, respectively).<br />Conclusions: No benefit of MBP was found regarding morbidity and mortality after anastomotic leakage in elective colorectal surgery.<br /> (Copyright © 2011 Elsevier Inc. All rights reserved.)
- Subjects :
- Adult
Aged
Aged, 80 and over
Anastomotic Leak etiology
Cardiotonic Agents administration & dosage
Colorectal Neoplasms surgery
Elective Surgical Procedures
Female
Humans
Intensive Care Units
Irritable Bowel Syndrome surgery
Length of Stay
Male
Middle Aged
Morbidity
Reoperation statistics & numerical data
Respiration, Artificial
Severity of Illness Index
Treatment Outcome
Anastomotic Leak mortality
Cathartics administration & dosage
Colonic Diseases surgery
Digestive System Surgical Procedures adverse effects
Digestive System Surgical Procedures mortality
Rectal Diseases surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1879-1883
- Volume :
- 202
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- American journal of surgery
- Publication Type :
- Academic Journal
- Accession number :
- 21871987
- Full Text :
- https://doi.org/10.1016/j.amjsurg.2010.10.018