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Atrial fibrillation hospitalization is not increased with short-term elevations in exposure to fine particulate air pollution.
- Source :
-
Pacing and clinical electrophysiology : PACE [Pacing Clin Electrophysiol] 2011 Nov; Vol. 34 (11), pp. 1475-9. - Publication Year :
- 2011
-
Abstract
- Background: Previous studies have observed that short-term exposure to elevated concentrations of particulate matter (PM) air pollution increases risk of acute ischemic heart disease events and heart failure hospitalization, alters cardiac autonomic function, and increases risk of arrhythmias. This study explored the potential associations between short-term elevations in PM exposure and atrial fibrillation (AF).<br />Methods and Results: A case-crossover study design was used to explore associations between fine PM (PM2.5, particles with an aerodynamic diameter ≤2.5 μm) and 10,457 AF hospitalizations from 1993 to 2008 of patients who lived on Utah’s Wasatch Front. Patients were hospitalized at Intermountain Healthcare facilities with a primary diagnosis of AF. Concurrent day exposure and cumulative lagged exposures for up to 21 days were explored and the data were stratified by sex, age, and previous or subsequent admission for myocardial infarction. Although the estimated associations between PM2.5 and AF hospitalizations for the various lag structures and strata were consistently positive suggestive of risk, they were not statistically significant and they were extremely small compared to previously observed associations with ischemic heart disease events and heart failure hospitalizations. Further, we observed no additive risk between PM2.5 and AF hospitalization in those with respiratory disease or sleep apnea.<br />Conclusions: Unlike previously observed associations with ischemic heart disease events and heart failure hospitalizations using similar study design and approaches, this study found that hospitalization for AF was not significantly associated with elevations in short-term exposure to fine PM air pollution.
- Subjects :
- Adult
Aged
Aged, 80 and over
Environmental Exposure analysis
Female
Humans
Male
Middle Aged
Prevalence
Risk Assessment
Risk Factors
Utah epidemiology
Altitude
Atrial Fibrillation epidemiology
Environmental Exposure statistics & numerical data
Hospitalization statistics & numerical data
Particulate Matter analysis
Subjects
Details
- Language :
- English
- ISSN :
- 1540-8159
- Volume :
- 34
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Pacing and clinical electrophysiology : PACE
- Publication Type :
- Academic Journal
- Accession number :
- 21895725
- Full Text :
- https://doi.org/10.1111/j.1540-8159.2011.03200.x