Alkaloids from Hippeastrum morelianum Lem. (Amaryllidaceae).

Authors :: Giordani RB
de Andrade JP
Verli H
Dutilh JH
Henriques AT
Berkov S
Bastida J
Zuanazzi JA
Source :: Magnetic resonance in chemistry : MRC [Magn Reson Chem] 2011 Oct; Vol. 49 (10), pp. 668-72. Date of Electronic Publication: 2011 Sep 06.
Publication Year :: 2011
Abstract: The Amaryllidaceae family has proven to be a rich source of active molecules. As part of an ongoing project, we report a phytochemical study of Hippeastrum morelianum (Amaryllidaceae), from which we have isolated two homolycorine-type alkaloids, the new 2α,7-dimethoxyhomolycorine (1) and the poorly described candimine (2), as well as six known alkaloids: tazettine, pretazettine, 3-epimacronine, haemanthamine, hamayne and trisphaeridine. For reference purposes, the NMR of the isolated compounds was unequivocally described, based on 2D NMR measurements including (1)H-(1)H COSY, (1)H-(1)H NOESY, HSQC and HMBC.<br /> (Copyright © 2011 John Wiley & Sons, Ltd.)