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[Structural changes in the DNA of the blood nucleotides and the development of late sequelae in irradiated rats].
- Source :
-
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1990 Mar; Vol. 109 (3), pp. 296-9. - Publication Year :
- 1990
-
Abstract
- Fluorescent analysis of structural changes of nucleotide in the blood associated with AT fragments has been studied in rats, gamma-irradiated with doses of 2 and 4 Gy. It was demonstrated that the haematological, gerontological and cancerogenic late consequences were preceded by the structural genomic disturbances determined by 30 day after irradiation.
- Subjects :
- Animals
DNA blood
DNA genetics
Ethidium
Fluorescent Dyes
Gamma Rays
Indoles
Leukocytes radiation effects
Male
Nucleotides blood
Nucleotides genetics
Radiation Injuries, Experimental etiology
Radiation Injuries, Experimental genetics
Radiation Injuries, Experimental mortality
Radiation Injuries, Experimental pathology
Rats
Time Factors
Whole-Body Irradiation
DNA radiation effects
Nucleotides radiation effects
Radiation Injuries, Experimental blood
Subjects
Details
- Language :
- Russian
- ISSN :
- 0365-9615
- Volume :
- 109
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Biulleten' eksperimental'noi biologii i meditsiny
- Publication Type :
- Academic Journal
- Accession number :
- 2194584