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Modulable Southern and Northern blot hybridization apparatus for routine screening of gene amplification and expression.

Authors :
Bignon C
Roux-Dosseto M
Lissitzky JC
Martin PM
Source :
Journal of biochemical and biophysical methods [J Biochem Biophys Methods] 1990 Apr-May; Vol. 20 (4), pp. 293-302.
Publication Year :
1990

Abstract

An apparatus for Northern and Southern blot hybridization is described. It allows from one to twenty-four blots to be processed at the same time, with different probes. All the pre-, post- and hybridization steps are performed without handling the filters and the experimenter is totally protected from beta radiations. The development of such modulable materials has become necessary since Southern and Northern techniques are becoming routine assays in hospitals, particularly in the field of oncology, in prognosis and for hereditary diseases, as an antenatal diagnosis procedure.

Details

Language :
English
ISSN :
0165-022X
Volume :
20
Issue :
4
Database :
MEDLINE
Journal :
Journal of biochemical and biophysical methods
Publication Type :
Academic Journal
Accession number :
2195094
Full Text :
https://doi.org/10.1016/0165-022x(90)90091-p