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Complementary screening techniques yielded fragments that inhibit the phosphatase activity of soluble epoxide hydrolase.
- Source :
-
ChemMedChem [ChemMedChem] 2011 Dec 09; Vol. 6 (12), pp. 2146-9. Date of Electronic Publication: 2011 Oct 21. - Publication Year :
- 2011
- Subjects :
- Computer Simulation
Drug Evaluation, Preclinical
Enzyme Activation drug effects
Epoxide Hydrolases metabolism
Fluorescent Dyes chemistry
Kinetics
Protein Structure, Tertiary
Substrate Specificity
Enzyme Inhibitors chemistry
Enzyme Inhibitors pharmacology
Epoxide Hydrolases antagonists & inhibitors
Subjects
Details
- Language :
- English
- ISSN :
- 1860-7187
- Volume :
- 6
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- ChemMedChem
- Publication Type :
- Academic Journal
- Accession number :
- 22021219
- Full Text :
- https://doi.org/10.1002/cmdc.201100433