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Bacteremia and MR-proANP changes in mild community-acquired pneumonia.

Authors :
Guinard-Barbier S
Chenevier-Gobeaux C
Grabar S
Quinquis L
Schmidt J
Hausfater P
Casalino E
Huet S
Pourriat JL
Renaud B
Claessens YE
Source :
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2011 Dec; Vol. 16 (8), pp. 637-41.
Publication Year :
2011

Abstract

Background: Mid-regional pro-atrial natriuretic peptide (MR-proANP) increases with severity in community-acquired pneumonia (CAP). We investigated whether changes of MR-proANP correlated to bacteremia.<br />Methods: 392 adult patients with CAP visiting emergency department from a prospective observational multicenter study.<br />Results: MR-proANP levels increased in patients with positive bacteremia (92.8 pmol/L vs. 84.3 pmol/L, pā€‰=ā€‰0.04). Performance of MR-proANP to detect bacteremia (0.60) was equivalent to CRP (0.59) but less accurate than PCT (0.69).<br />Conclusion: MR-ANP poorly predicts bacteremia in CAP patients.

Details

Language :
English
ISSN :
1366-5804
Volume :
16
Issue :
8
Database :
MEDLINE
Journal :
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
Publication Type :
Academic Journal
Accession number :
22103585
Full Text :
https://doi.org/10.3109/1354750X.2011.620629