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One-year survival of demented stroke patients: data from the Dijon Stroke Registry, France (1985-2008).
- Source :
-
European journal of neurology [Eur J Neurol] 2012 May; Vol. 19 (5), pp. 712-7. Date of Electronic Publication: 2011 Dec 05. - Publication Year :
- 2012
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Abstract
- Background and Purpose: Dementia is a frequent condition after stroke that may affect the prognosis of patients. Our aim was to determine whether post-stroke dementia was a predictor of 1-year case-fatality and to evaluate factors that could influence survival in demented stroke patients.<br />Methods: From 1985 to 2008, all first-ever strokes were recorded in the population-based stroke registry of Dijon, France (150, 000 inhabitants). Dementia was diagnosed during the first month following stroke, according to DSM-III and DSM-IV criteria. Survival was evaluated at 1 year and multivariate analyses were performed using Cox proportional hazards to identify independent predictive factors.<br />Results: We recorded 3948 first-ever strokes. Among these stroke patients, 3201 (81%) were testable, and of these, 653 (20.4%) had post-stroke dementia (337 women and 316 men). Demented patients had lower 1-year survival than patients without dementia (82.9% vs. 86.9%, P = 0.013). However, in multivariate analysis, dementia did not appear as an independent predictor of 1-year death. In demented stroke patients, age >80 years old, severe handicap at discharge, recurrent stroke within the first year and subarachnoid haemorrhage were associated with a higher risk of 1-year death, and the risk was lower in the study period 2003-2008.<br />Conclusions: Dementia after stroke is not independently associated with an increased risk of death at 1 year. In recent years, 1-year case-fatality decreased in demented as well as in and non-demented patients suggesting that improvements in the management of stroke also benefited the most fragile patients.<br /> (© 2011 The Author(s). European Journal of Neurology © 2011 EFNS.)
- Subjects :
- Adult
Age Factors
Aged
Aged, 80 and over
Analysis of Variance
Female
Follow-Up Studies
France epidemiology
Humans
Male
Middle Aged
Neuropsychological Tests
Registries statistics & numerical data
Retrospective Studies
Risk Factors
Stroke complications
Survival Rate
Time Factors
Dementia epidemiology
Dementia mortality
Stroke epidemiology
Stroke mortality
Subjects
Details
- Language :
- English
- ISSN :
- 1468-1331
- Volume :
- 19
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- European journal of neurology
- Publication Type :
- Academic Journal
- Accession number :
- 22136138
- Full Text :
- https://doi.org/10.1111/j.1468-1331.2011.03613.x