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[Th1, Th17 and Th1+17 cells].

Authors :
Chang HD
Kamradt T
Schulze-Koops H
Source :
Zeitschrift fur Rheumatologie [Z Rheumatol] 2011 Dec; Vol. 70 (10), pp. 862-5.
Publication Year :
2011

Abstract

T helper cells contribute to the induction and maintenance of rheumatic inflammation through the secretion of cytokines. The analysis of Th1 cells expressing interferon-γ, Th17 cells expressing interleukin-17 and the newly described Th1+17 cells could give insight into the pathophysiological mechanisms of rheumatic diseases. This could lead to the development of novel, targeted therapeutic strategies.

Details

Language :
German
ISSN :
1435-1250
Volume :
70
Issue :
10
Database :
MEDLINE
Journal :
Zeitschrift fur Rheumatologie
Publication Type :
Academic Journal
Accession number :
22139205
Full Text :
https://doi.org/10.1007/s00393-011-0779-5