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Wells' syndrome associated with churg-strauss syndrome.

Authors :
Lee SH
Roh MR
Jee H
Chung KY
Jung JY
Source :
Annals of dermatology [Ann Dermatol] 2011 Nov; Vol. 23 (4), pp. 497-500. Date of Electronic Publication: 2011 Nov 03.
Publication Year :
2011

Abstract

Churg-Strauss syndrome (CSS) is a multisystem granulomatous vasculitis that is characterized by peripheral eosinophilia and the infiltration of eosinophils into systemic organs. The skin lesions of CSS consist mainly of palpable purpura and nodules. Wells' syndrome (WS) is a rare inflammatory dermatosis that is associated with recurrent granulomatous dermatitis and eosinophilia. Since these two diseases are rare, any overlap between them is very unusual. Herein, we report a patient with CSS, who initially presented a skin eruption of erythematous urticarial-plaques, vesicles, and blisters. Upon biopsy, the histology of these plaques indicated eosinophilic infiltration and "flame figures" within the dermis, which was consistent with a diagnosis of WS. Although the association between WS and CSS that was observed in our patient may be purely coincidental, it could also suggest a common pathogenetic background of these two distinct diseases, as both share several many common features.

Details

Language :
English
ISSN :
2005-3894
Volume :
23
Issue :
4
Database :
MEDLINE
Journal :
Annals of dermatology
Publication Type :
Report
Accession number :
22148019
Full Text :
https://doi.org/10.5021/ad.2011.23.4.497