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Weaving the web of ER tubules.

Authors :
Hu J
Prinz WA
Rapoport TA
Source :
Cell [Cell] 2011 Dec 09; Vol. 147 (6), pp. 1226-31.
Publication Year :
2011

Abstract

How is the characteristic shape of an organelle generated? Recent work has provided insight into how the tubular network of the endoplasmic reticulum (ER) is formed. The tubules themselves are shaped by the reticulons and DP1/Yop1p, whereas their fusion into a network is brought about by membrane-bound GTPases that include the atlastins, Sey1p, and RHD3.<br /> (Copyright © 2011 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1097-4172
Volume :
147
Issue :
6
Database :
MEDLINE
Journal :
Cell
Publication Type :
Academic Journal
Accession number :
22153070
Full Text :
https://doi.org/10.1016/j.cell.2011.11.022