Rapid radiographic and clinical improvement after treatment of a MET-amplified recurrent glioblastoma with a mesenchymal-epithelial transition inhibitor.

Subjects

Subjects :

Brain Neoplasms diagnostic imaging
Brain Neoplasms genetics
Brain Neoplasms pathology
Crizotinib
Female
Gene Amplification
Glioblastoma diagnostic imaging
Glioblastoma genetics
Glioblastoma pathology
Humans
Middle Aged
Proto-Oncogene Proteins c-met genetics
Radiography
Brain Neoplasms drug therapy
Epithelial-Mesenchymal Transition drug effects
Glioblastoma drug therapy
Pyrazoles therapeutic use
Pyridines therapeutic use

Details

Language :

English

ISSN :

1527-7755

Volume :

30

Issue :

3

Database :

MEDLINE

Journal :

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Publication Type :

Academic Journal

Accession number :

22162573

Full Text :

https://doi.org/10.1200/JCO.2011.38.4586