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[Methodic approaches to treatment of the chronic generalized parodontitis in elderly and senile patients].
- Source :
-
Advances in gerontology = Uspekhi gerontologii [Adv Gerontol] 2011; Vol. 24 (3), pp. 515-20. - Publication Year :
- 2011
-
Abstract
- A comprehensive treatment with Likopid of chronic generalized parodontitis in 114 elderly and senile patients was carried out. The state of mechanisms of innate immunity (phagocytosis mechanisms) as well as the profile of proinflammatory cytokines was assessed. The effect of antibiotic-resistant strains of prior microflora on the combined therapy of patients of different age with chronic generalized parodontitis was studied. It is established that due to presence of various types of opportunistic pathogens in patients of different age with parodontitis using the prophylactic antibiotics for the empirical (to determine the antibiotic resistance), a combination of Metronidazole and Lincomycin with the mandatory appointment of immunomodulatory drugs for activation of monocyte-phagocytic system of the patient elderly is most advisable. Use of the drug , "Likopid" significantly improves the results of treatment the elderly and old patients with chronic generalized parodonthitis.
- Subjects :
- Acetylmuramyl-Alanyl-Isoglutamine therapeutic use
Adult
Aged
Chronic Periodontitis immunology
Chronic Periodontitis physiopathology
Cytokines immunology
Drug Resistance, Microbial
Female
Humans
Immunologic Factors therapeutic use
Lincomycin therapeutic use
Male
Metronidazole therapeutic use
Microbial Sensitivity Tests
Middle Aged
Monitoring, Immunologic
Periodontium immunology
Periodontium microbiology
Severity of Illness Index
Treatment Outcome
Acetylmuramyl-Alanyl-Isoglutamine analogs & derivatives
Anti-Bacterial Agents therapeutic use
Antibiotic Prophylaxis methods
Chronic Periodontitis drug therapy
Combined Modality Therapy methods
Periodontium drug effects
Phagocytosis drug effects
Subjects
Details
- Language :
- Russian
- ISSN :
- 1561-9125
- Volume :
- 24
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Advances in gerontology = Uspekhi gerontologii
- Publication Type :
- Academic Journal
- Accession number :
- 22184987