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Kinetochore dynamics: how protein dynamics affect chromosome segregation.

Authors :
Dorn JF
Maddox PS
Source :
Current opinion in cell biology [Curr Opin Cell Biol] 2012 Feb; Vol. 24 (1), pp. 57-63. Date of Electronic Publication: 2011 Dec 29.
Publication Year :
2012

Abstract

Protein dynamics generate adaptive cellular architecture. This concept is exemplified by kinetochores, organelles that orchestrate chromosome segregation during mitosis. In this review, we will focus on protein dynamics at kinetochores and discuss how these dynamics impact chromosome motility during mitosis.<br /> (Copyright © 2012 Elsevier Ltd. All rights reserved.)

Details

Language :
English
ISSN :
1879-0410
Volume :
24
Issue :
1
Database :
MEDLINE
Journal :
Current opinion in cell biology
Publication Type :
Academic Journal
Accession number :
22209729
Full Text :
https://doi.org/10.1016/j.ceb.2011.12.003