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Structures of two new phenolic glycosides, kaempferiaosides A and B, and hepatoprotective constituents from the rhizomes of Kaempferia parviflora.
- Source :
-
Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2012; Vol. 60 (1), pp. 62-9. - Publication Year :
- 2012
-
Abstract
- Two new phenolic glycosides, kaempferiaosides A and B were isolated from the rhizomes of Kaempferia parviflora (Zingiberaceae) together with 24 known compounds. Their structures including absolute stereochemistry were elucidated on the basis of chemical and spectroscopic evidence. Among the isolates, 5,3'-dihydroxy-3,7,4'-trimethoxyflavone showed higher activity than silybin, a commercial hepatoprotective agent.
- Subjects :
- Animals
Cells, Cultured
Glycosides isolation & purification
Glycosides pharmacology
Magnetic Resonance Spectroscopy
Mice
Molecular Conformation
Phenols isolation & purification
Protective Agents isolation & purification
Rhizome chemistry
Glycosides chemistry
Hepatocytes drug effects
Phenols chemistry
Phenols pharmacology
Protective Agents chemistry
Protective Agents pharmacology
Zingiberaceae chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1347-5223
- Volume :
- 60
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Chemical & pharmaceutical bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 22223376
- Full Text :
- https://doi.org/10.1248/cpb.60.62