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Structures of two new phenolic glycosides, kaempferiaosides A and B, and hepatoprotective constituents from the rhizomes of Kaempferia parviflora.

Authors :
Chaipech S
Morikawa T
Ninomiya K
Yoshikawa M
Pongpiriyadacha Y
Hayakawa T
Muraoka O
Source :
Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2012; Vol. 60 (1), pp. 62-9.
Publication Year :
2012

Abstract

Two new phenolic glycosides, kaempferiaosides A and B were isolated from the rhizomes of Kaempferia parviflora (Zingiberaceae) together with 24 known compounds. Their structures including absolute stereochemistry were elucidated on the basis of chemical and spectroscopic evidence. Among the isolates, 5,3'-dihydroxy-3,7,4'-trimethoxyflavone showed higher activity than silybin, a commercial hepatoprotective agent.

Details

Language :
English
ISSN :
1347-5223
Volume :
60
Issue :
1
Database :
MEDLINE
Journal :
Chemical & pharmaceutical bulletin
Publication Type :
Academic Journal
Accession number :
22223376
Full Text :
https://doi.org/10.1248/cpb.60.62