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[Analysis association of acute ischemic stroke and DNA markers in Russian and Moldavian populations].

Authors :
Bondarenko EA
Shetova IM
Shamalov NA
Mokan EI
Barbakar NI
Kurochkin GS
Protopop SS
Lysyĭ LT
SlominskIĭ PA
Limborskaia SA
Skvortsova VI
Source :
Genetika [Genetika] 2011 Oct; Vol. 47 (10), pp. 1393-401.
Publication Year :
2011

Abstract

Polymorphisms c.202G > A of prothrombin F2 gene, c.1691G > A of coagulation factor V F5 gene, c.675delinsG of plasminogen activator1 gene, and (-5)T > C Kozak gene of thrombocytic receptor were studied in the Russian and Moldavian ethnic groups. We have found no association between these polymorphisms and the risk of ischemic stroke development in both ethnic groups. No association was revealed between the risk of stroke development and various combinations of the single nucleotide polymorphisms examined in the sample of ischemic stroke patients from Russia.

Details

Language :
Russian
ISSN :
0016-6758
Volume :
47
Issue :
10
Database :
MEDLINE
Journal :
Genetika
Publication Type :
Academic Journal
Accession number :
22232928