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Diabetic retinopathy in the SEARCH for Diabetes in Youth Cohort: a pilot study.
- Source :
-
Diabetic medicine : a journal of the British Diabetic Association [Diabet Med] 2012 Sep; Vol. 29 (9), pp. 1148-52. - Publication Year :
- 2012
-
Abstract
- Aims: The aim of this pilot study was to generate an initial estimate of the prevalence and correlates of diabetic retinopathy in a racially and ethnically diverse sample of youth with Type 1 and Type 2 diabetes mellitus.<br />Methods: A pilot study was conducted among 222 individuals with Type 1 diabetes (79% non-Hispanic white, 21% other) and 43 with Type 2 diabetes (28% non-Hispanic white, 72% other), all of > 5 years duration (mean duration 6.8 years) who participated in the SEARCH for Diabetes in Youth study. Diabetic retinopathy was assessed using non-mydriatic retinal photography of both eyes.<br />Results: The prevalence of diabetic retinopathy was 17% for Type 1 diabetes and 42% for Type 2 diabetes (odds ratio 1.50, 95% CI 0.58-3.88; P = 0.40 adjusted for age, duration, gender, race/ethnicity, parental education and HbA(1c). HbA(1c) was significantly higher among those with any diabetic retinopathy (adjusted mean 79 mmol/mol, 9.4%) vs. no diabetic retinopathy (adjusted mean 70 mmol/mol, 8.6%) (P = 0.015). LDL cholesterol was also significantly higher among those with any diabetic retinopathy (adjusted mean 107.2 mg/dl) compared with those without diabetic retinopathy (adjusted mean 97.9 mg/dl) (P = 0.04).<br />Conclusions: The prevalence of diabetic retinopathy in contemporary young individuals was substantial, particularly among minority youth and those with Type 2 diabetes. Further long-term study of diabetic retinopathy in youth is needed.<br /> (© 2012 The Authors. Diabetic Medicine © 2012 Diabetes UK.)
- Subjects :
- Adolescent
Child
Cohort Studies
Diabetes Mellitus, Type 1 ethnology
Diabetes Mellitus, Type 2 ethnology
Diabetic Retinopathy ethnology
Humans
Minority Groups
Pilot Projects
Prevalence
United States epidemiology
White People ethnology
Young Adult
Diabetes Mellitus, Type 1 complications
Diabetes Mellitus, Type 2 complications
Diabetic Retinopathy epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1464-5491
- Volume :
- 29
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Diabetic medicine : a journal of the British Diabetic Association
- Publication Type :
- Academic Journal
- Accession number :
- 22269205
- Full Text :
- https://doi.org/10.1111/j.1464-5491.2012.03591.x