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Diverse mobilized class 1 integrons are common in the chromosomes of pathogenic Pseudomonas aeruginosa clinical isolates.
- Source :
-
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2012 Apr; Vol. 56 (4), pp. 2169-72. Date of Electronic Publication: 2012 Jan 23. - Publication Year :
- 2012
-
Abstract
- Eleven clinical class 1 integron-containing Pseudomonas aeruginosa isolates from Australia and Uruguay were investigated for the genomic locations of these elements. Several novel class 1 integrons/transposons were found in at least four distinct locations in the chromosome, including genomic islands. These elements seem to be undergoing successful dispersal by lateral gene transfer since integrons were identified across several lineages and more than one clonal line.
- Subjects :
- Australia
Drug Resistance, Bacterial genetics
Drug Resistance, Multiple, Bacterial drug effects
Electrophoresis, Gel, Pulsed-Field
Genes, Bacterial genetics
Genomic Islands genetics
Microbial Sensitivity Tests
Molecular Sequence Data
Polymerase Chain Reaction
Pseudomonas Infections genetics
Uruguay
Chromosomes, Bacterial genetics
Integrons genetics
Pseudomonas Infections microbiology
Pseudomonas aeruginosa genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1098-6596
- Volume :
- 56
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Antimicrobial agents and chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 22271862
- Full Text :
- https://doi.org/10.1128/AAC.06048-11