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Mn loaded apoferritin as an MRI sensor of melanin formation in melanoma cells.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2012 Feb 28; Vol. 48 (18), pp. 2436-8. Date of Electronic Publication: 2012 Jan 25. - Publication Year :
- 2012
-
Abstract
- Mn(III)-loaded apoferritin is promptly reduced to Mn(II)-apoferritin by the oxidation of L-DOPA to melanin. The process is nicely witnessed by a marked relaxation enhancement of water proton relaxation rate that has been detected both in cultured melanoma cells and in tumor animal models.<br /> (This journal is © The Royal Society of Chemistry 2012)
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 48
- Issue :
- 18
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 22273600
- Full Text :
- https://doi.org/10.1039/c2cc17801j