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Prevalence of item level negative symptoms in first episode psychosis diagnoses.
- Source :
-
Schizophrenia research [Schizophr Res] 2012 Mar; Vol. 135 (1-3), pp. 128-33. Date of Electronic Publication: 2012 Jan 27. - Publication Year :
- 2012
-
Abstract
- Unlabelled: The relevance of negative symptoms across the diagnostic spectrum of the psychoses remains uncertain. The purpose of this study was to report on prevalence of item and subscale level negative symptoms across the first episode psychosis (FEP) diagnostic spectrum in an epidemiological sample, and to ascertain whether items and subscales were more prevalent in a schizophrenia spectrum diagnoses group compared to an 'all other psychotic diagnoses' group. We measured negative symptoms in 330 patients presenting with FEP using the Scale for Assessment of Negative Symptoms (SANS), and ascertained diagnosis using the Structured Clinical Interview for DSM IV. Prevalence of SANS items and subscales were tabulated across all psychotic diagnoses, and logistic regression analysis determined which items and subscales were predictive of schizophrenia spectrum diagnoses. SANS items were most prevalent in schizophrenia spectrum conditions but frequently presented in other FEP diagnoses, particularly substance induced psychotic disorder and Major Depressive Disorder. Brief psychotic disorder and bipolar disorders had low levels of negative symptoms. SANS items and subscales which significantly predicted schizophrenia spectrum diagnoses, were also frequently present in some of the other psychotic diagnoses.<br />Conclusions: SANS items have high prevalence in FEP, and while commonest in schizophrenia spectrum conditions are not restricted to this diagnostic subgroup.<br /> (Copyright © 2012 Elsevier B.V. All rights reserved.)
- Subjects :
- Adolescent
Adult
Aged
Bipolar Disorder diagnosis
Depressive Disorder, Major diagnosis
Female
Humans
Ireland epidemiology
Male
Middle Aged
Prevalence
Psychiatric Status Rating Scales
Retrospective Studies
Schizophrenia diagnosis
Schizophrenia, Paranoid diagnosis
Severity of Illness Index
Young Adult
Bipolar Disorder epidemiology
Depressive Disorder, Major epidemiology
Psychotic Disorders classification
Psychotic Disorders diagnosis
Psychotic Disorders epidemiology
Schizophrenia epidemiology
Schizophrenia, Paranoid epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1573-2509
- Volume :
- 135
- Issue :
- 1-3
- Database :
- MEDLINE
- Journal :
- Schizophrenia research
- Publication Type :
- Academic Journal
- Accession number :
- 22281102
- Full Text :
- https://doi.org/10.1016/j.schres.2012.01.004