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Partial radiofrequency ablation of the spleen in thalassemia.
- Source :
-
Diagnostic and interventional radiology (Ankara, Turkey) [Diagn Interv Radiol] 2012 Jul-Aug; Vol. 18 (4), pp. 397-402. Date of Electronic Publication: 2012 Feb 13. - Publication Year :
- 2012
-
Abstract
- Purpose: To investigate the efficiency of partial radiofrequency ablation of the spleen in patients with thalassemia major and intermedia.<br />Materials and Methods: Partial radiofrequency ablation of the spleen was performed in 19 thalassemic patients (10 females, nine males) with a mean age of 12.7 years (age range, 7-30 years). This group of patients consisted of 11 patients with thalassemia major and nine with thalassemia intermedia. The procedure was performed under intravenous sedation and was complete in 29-35 min.<br />Results: The ratio of the ablated volume to the whole spleen ranged from 5.3% to 23% (mean, 9.83 ± 5.56%). A significant increase was found in the platelet count after radiofrequency ablation of the spleen (P = 0.002). No statistically significant difference was found in hemoglobin levels (P = 0.171) or transfusion intervals (P = 0.054) before and after radiofrequency ablation. Additionally, no statistically significant relationship was observed between the ablation ratio and hemoglobin levels (P = 0.233) and between the ablation ratio and transfusion interval (P = 0.822). No major complication occurred due to this interventional procedure.<br />Conclusion: A single percutaneous radiofrequency ablation of the spleen reduces thrombocytopenia in thalassemic patients with splenomegaly but does not change the hemoglobin levels or transfusion intervals.
- Subjects :
- Adolescent
Adult
Child
Cohort Studies
Contrast Media
Female
Follow-Up Studies
Humans
Male
Postoperative Complications diagnostic imaging
Postoperative Complications physiopathology
Prospective Studies
Radiography, Interventional methods
Risk Assessment
Severity of Illness Index
Time Factors
Treatment Outcome
Ultrasonography, Doppler
Young Adult
Catheter Ablation methods
Radiographic Image Enhancement
Splenectomy methods
Tomography, X-Ray Computed methods
beta-Thalassemia diagnostic imaging
beta-Thalassemia surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1305-3612
- Volume :
- 18
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Diagnostic and interventional radiology (Ankara, Turkey)
- Publication Type :
- Academic Journal
- Accession number :
- 22328281
- Full Text :
- https://doi.org/10.4261/1305-3825.DIR.4537-11.1