XmAb-5574 antibody demonstrates superior antibody-dependent cellular cytotoxicity as compared with CD52- and CD20-targeted antibodies in adult acute lymphoblastic leukemia cells.

Authors :: Rafiq S
Cheney C
Mo X
Jarjoura D
Muthusamy N
Byrd JC
Source :: Leukemia [Leukemia] 2012 Jul; Vol. 26 (7), pp. 1720-2. Date of Electronic Publication: 2012 Feb 15.
Publication Year :: 2012

Subjects :: Adult
CD52 Antigen
Flow Cytometry
Humans
Immunoglobulin Fc Fragments metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma immunology
Precursor Cell Lymphoblastic Leukemia-Lymphoma pathology
Receptors, IgG immunology
Receptors, IgG metabolism
Antibodies, Monoclonal pharmacology
Antibody-Dependent Cell Cytotoxicity
Antigens, CD immunology
Antigens, CD19 immunology
Antigens, CD20 immunology
Antigens, Neoplasm immunology
Glycoproteins immunology
Immunoglobulin Fc Fragments immunology
Precursor Cell Lymphoblastic Leukemia-Lymphoma drug therapy

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