Back to Search
Start Over
A developmental and genetic classification for malformations of cortical development: update 2012.
- Source :
-
Brain : a journal of neurology [Brain] 2012 May; Vol. 135 (Pt 5), pp. 1348-69. Date of Electronic Publication: 2012 Mar 16. - Publication Year :
- 2012
-
Abstract
- Malformations of cerebral cortical development include a wide range of developmental disorders that are common causes of neurodevelopmental delay and epilepsy. In addition, study of these disorders contributes greatly to the understanding of normal brain development and its perturbations. The rapid recent evolution of molecular biology, genetics and imaging has resulted in an explosive increase in our knowledge of cerebral cortex development and in the number and types of malformations of cortical development that have been reported. These advances continue to modify our perception of these malformations. This review addresses recent changes in our perception of these disorders and proposes a modified classification based upon updates in our knowledge of cerebral cortical development.
- Subjects :
- Cell Movement physiology
Developmental Disabilities etiology
Diagnostic Imaging
Epilepsy etiology
History, 21st Century
Humans
Molecular Biology
Cerebral Cortex abnormalities
Cerebral Cortex growth & development
Cerebral Cortex pathology
Malformations of Cortical Development classification
Malformations of Cortical Development complications
Malformations of Cortical Development genetics
Mutation genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1460-2156
- Volume :
- 135
- Issue :
- Pt 5
- Database :
- MEDLINE
- Journal :
- Brain : a journal of neurology
- Publication Type :
- Academic Journal
- Accession number :
- 22427329
- Full Text :
- https://doi.org/10.1093/brain/aws019