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Progression of outflow tract obstruction in the fetus.
- Source :
-
Early human development [Early Hum Dev] 2012 May; Vol. 88 (5), pp. 279-85. Date of Electronic Publication: 2012 Mar 27. - Publication Year :
- 2012
-
Abstract
- Fetal ventricular outflow tract obstruction (OTO) is congenital heart disease with significant potential for progression before birth as a consequence of the unique nature of the fetal circulation. The pattern of evolution depends upon the timing of development, severity of obstruction and the influence of the OTO on the fetal atrioventricular valve and myocardial function. Critical aortic (AS) or pulmonary (PS) valve stenosis, the two most common forms of fetal OTO, may be associated with progressive ventricular and great artery hypoplasia if presenting early in gestation or with normal ventricular and great artery growth if evolving later in gestation. In some affected fetuses, AS or PS may lead to the evolution of fetal heart failure. This article will review our current understanding of the natural history of fetal AS and PS, experience with fetal intervention and future directions of research.<br /> (Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.)
- Subjects :
- Female
Fetal Diseases surgery
Fetoscopy
Gestational Age
Humans
Pregnancy
Ultrasonography
Ventricular Outflow Obstruction congenital
Ventricular Outflow Obstruction embryology
Ventricular Outflow Obstruction surgery
Fetal Diseases diagnostic imaging
Guidelines as Topic
Ventricular Outflow Obstruction diagnostic imaging
Subjects
Details
- Language :
- English
- ISSN :
- 1872-6232
- Volume :
- 88
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Early human development
- Publication Type :
- Academic Journal
- Accession number :
- 22460060
- Full Text :
- https://doi.org/10.1016/j.earlhumdev.2012.02.005