Back to Search
Start Over
The risk of gestational diabetes mellitus among Mexican women with a history of infertility and polycystic ovary syndrome.
- Source :
-
Fertility and sterility [Fertil Steril] 2012 Jun; Vol. 97 (6), pp. 1467-71. Date of Electronic Publication: 2012 Apr 13. - Publication Year :
- 2012
-
Abstract
- Objective: To study the incidence of gestational diabetes mellitus (GDM) in Mexican women with a history of infertility and polycystic ovary syndrome (PCOS) compared with women without PCOS matched by age, pregestational body mass index (BMI), and parity.<br />Design: Historic cohort study.<br />Setting: Level three medical institution.<br />Patient(s): Group 1 (n = 52), women with a history of infertility and PCOS, and group 2 (n = 52), women without PCOS. Inclusion criteria were singleton pregnancy with ≤ 13 weeks of gestation. Exclusion criteria were pregestational diabetes mellitus and/or concomitant diseases.<br />Intervention(s): Diagnosis of GDM was based on a 3-hour, 100-g oral glucose tolerance test (GTT) performed during the second trimester.<br />Main Outcome Measure(s): Incidence and relative risk (RR) for GDM.<br />Result(s): The incidence of GDM was 26.9% and 9.6% for groups 1 and 2, respectively (RR = 2.8; 95% confidence interval 1.08-7.2). No other between-group differences were observed in the incidence of miscarriage, preterm birth, premature rupture of membranes, preeclampsia, stillbirth, fetal malformations, or small or large for gestational age newborns.<br />Conclusion(s): Pregnant Mexican women with a history of infertility and PCOS are at increased risk for developing GDM. This risk should be considered beginning early in the second trimester for a timely intervention and to improve the maternal-fetal prognosis.<br /> (Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1556-5653
- Volume :
- 97
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Fertility and sterility
- Publication Type :
- Academic Journal
- Accession number :
- 22503417
- Full Text :
- https://doi.org/10.1016/j.fertnstert.2012.03.023