The schizoictal syndrome.

Authors :: Biermann T
Sperling W
Source :: Medical hypotheses [Med Hypotheses] 2012 Jul; Vol. 79 (1), pp. 50-2. Date of Electronic Publication: 2012 Apr 28.
Publication Year :: 2012
Abstract: There are several common denominators of schizophrenia and epilepsy including models of pathogenesis as well as their clinical occurrence mainly referring to schizophrenia-like syndrome in epilepsy or similar clinical entities [1]. Up to now it has not been emphasized that a process of synchronization or desynchronization of neuronal cell structures within the context of neuronal plasticity might be a plausible pathogenetic mechanism of epilepsy as well as schizophrenia. Clinical as well as therapeutical implications of this hypothesis on the basis of scientific evidence are discussed.<br /> (Copyright © 2012 Elsevier Ltd. All rights reserved.)