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[Clinico-morphological properties and surgical treatment results in retroperitoneal liposarcomas].

Authors :
Nered SN
Stilidi IS
Klimenkov AA
Bolotskiĭ VI
Anurova OA
Source :
Voprosy onkologii [Vopr Onkol] 2012; Vol. 58 (1), pp. 94-100.
Publication Year :
2012

Abstract

The separate clinico-morphological features of nonorganic retroperitoneal liposarcoma (NRL) and their prognostic value were studied in 200 patients. The type of primary NRL is histologically erentiated in 65.5%, myxoid in 16.1%, dedifferentiated in 9.2%, pleomorphic in 4.6% and mixed in 2.3%. There is a positive elation between overall survival, lyposarcoma hystologic type < 0.007) and completeness of tumor resection (p < 0.0008). Differentiated and myxoid NRL with cell volume less than 5.0% are characterized by better prognosis. Myxoid NRL with cell volume more than 5.0%, dedifferentiated and pleomorphic NRL types are unfavorable prognostic factors. Radical surgical resectio leads to 5-year and 10-year overall survival of 57.5% and 7.8%. Palliative surgery lead to worse results with 3-year and 5-year overall survival of 50.0% and 31.8% respectively. Therefore, the most important prognostic factors in NRL are histological type and completeness of resection.

Details

Language :
Russian
ISSN :
0507-3758
Volume :
58
Issue :
1
Database :
MEDLINE
Journal :
Voprosy onkologii
Publication Type :
Academic Journal
Accession number :
22629837