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[Clinico-morphological properties and surgical treatment results in retroperitoneal liposarcomas].
- Source :
-
Voprosy onkologii [Vopr Onkol] 2012; Vol. 58 (1), pp. 94-100. - Publication Year :
- 2012
-
Abstract
- The separate clinico-morphological features of nonorganic retroperitoneal liposarcoma (NRL) and their prognostic value were studied in 200 patients. The type of primary NRL is histologically erentiated in 65.5%, myxoid in 16.1%, dedifferentiated in 9.2%, pleomorphic in 4.6% and mixed in 2.3%. There is a positive elation between overall survival, lyposarcoma hystologic type < 0.007) and completeness of tumor resection (p < 0.0008). Differentiated and myxoid NRL with cell volume less than 5.0% are characterized by better prognosis. Myxoid NRL with cell volume more than 5.0%, dedifferentiated and pleomorphic NRL types are unfavorable prognostic factors. Radical surgical resectio leads to 5-year and 10-year overall survival of 57.5% and 7.8%. Palliative surgery lead to worse results with 3-year and 5-year overall survival of 50.0% and 31.8% respectively. Therefore, the most important prognostic factors in NRL are histological type and completeness of resection.
- Subjects :
- Disease-Free Survival
Female
Humans
Liposarcoma mortality
Male
Middle Aged
Neoplasm Staging
Palliative Care methods
Prognosis
Retroperitoneal Neoplasms mortality
Retrospective Studies
Survival Analysis
Treatment Outcome
Liposarcoma pathology
Liposarcoma surgery
Retroperitoneal Neoplasms pathology
Retroperitoneal Neoplasms surgery
Subjects
Details
- Language :
- Russian
- ISSN :
- 0507-3758
- Volume :
- 58
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Voprosy onkologii
- Publication Type :
- Academic Journal
- Accession number :
- 22629837