Back to Search
Start Over
[Perceived morbidity and community burden of chikungunya in La Reunion].
- Source :
-
Medecine tropicale : revue du Corps de sante colonial [Med Trop (Mars)] 2012 Mar; Vol. 72 Spec No, pp. 76-82. - Publication Year :
- 2012
-
Abstract
- Background: Persistence of clinical manifestations, especially polyarthralgia and fatigue, is a characteristic feature of chikungunya virus (CHIK-v) infection. The purpose of this study was to measure the impact of prolonged or late-onset manifestations of CHIK-v infection on the self-perceived health of people on Reunion Island.<br />Methods: This retrospective cohort survey, dubbed TELECHIK survey, was conducted eighteen months after the end of the chikungunya outbreak on a representative random sample from the SEROCHIK population-based survey conducted on Reunion Island. A total of 1094 subjects whose CHIK-v specific IgG antibody status had been documented were interviewed about current symptoms.<br />Results: Analysis of data showed 45% of CHIK+ vs 14% of CHIK- subjects reporting musculoskeletal pain (P < 0.001), 56% vs. 44% reporting fatigue (P = 0.003), 77% vs. 53% reporting cerebral manifestations (P < 0.001), 51% vs. 34% reporting sensorineural impairments (P < 0.001), 18% vs. 13% reporting digestive complaints (P = 0.06), and 38% vs. 32% reporting skin involvement (P = 0.13). The mean delay between infection and interview was two years (range, 15-34 months). Analysis of data after correction for age, gender, body mass index and comorbidity indicated that rheumatic pain, fatigue, cerebral manifestations and sensorineural impairments were more likely in CHIK+ than CHIK- subjects but the likelihood of digestive and skin manifestations was the same.<br />Conclusion: With a mean delay of two years after infection, 45% to 77% of CHIK+ subjects reported prolonged or late-onset symptoms attributable to CHIK-v. These results indicate that persistent manifestations of chikungunya infection have a heavy impact on rheumatologic, neurological and sensorineural health.
- Subjects :
- Adolescent
Adult
Aged
Alphavirus Infections complications
Alphavirus Infections psychology
Chikungunya Fever
Cohort Studies
Community Health Services standards
Community Health Services supply & distribution
Cost of Illness
Data Collection
Female
Humans
Male
Middle Aged
Models, Biological
Morbidity
Population
Retrospective Studies
Reunion epidemiology
Telephone
Young Adult
Alphavirus Infections epidemiology
Community Health Services organization & administration
Perception physiology
Subjects
Details
- Language :
- French
- ISSN :
- 0025-682X
- Volume :
- 72 Spec No
- Database :
- MEDLINE
- Journal :
- Medecine tropicale : revue du Corps de sante colonial
- Publication Type :
- Academic Journal
- Accession number :
- 22693934