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Effect of high-oleic canola and flaxseed oils on energy expenditure and body composition in hypercholesterolemic subjects.
- Source :
-
Metabolism: clinical and experimental [Metabolism] 2012 Nov; Vol. 61 (11), pp. 1598-605. Date of Electronic Publication: 2012 Jun 12. - Publication Year :
- 2012
-
Abstract
- Objective: The fatty acid profile of dietary fats may contribute to its channelling toward oxidation versus storage, influencing energy and weight balance. Our objective was to compare the effects of diets enriched with high-oleic canola oil (HOCO), alone or blended with flaxseed oil (FXCO), on energy expenditure, substrate utilization, and body composition versus a typical Western diet (WD).<br />Materials/methods: Using a randomized crossover design, 34 hypercholesterolemic subjects (n=22 females) consumed 3 controlled diets for 28 days containing ~49% energy from carbohydrate, 14% energy from protein, and 37% energy from fat, of which 70% of fat was provided by HOCO rich in oleic acid, FXCO rich in alpha-linolenic acid, or WD rich in saturated fat. Indirect calorimetry measured energy expenditure and substrate oxidation. Body composition was analyzed by dual-energy x-ray absorptiometry.<br />Result: After 28 days, resting and postprandial energy expenditure and substrate oxidation were not different after consumption of the HOCO or FXCO diets compared with a typical Western diet. No significant changes in body composition measures were observed between diets. However, the android-to-gynoid ratio tended to increase (P=.055) after the FXCO diet compared with the HOCO diet.<br />Conclusions: The data suggest that substituting a typical Western dietary fatty acid profile with HOCO or FXCO does not significantly modulate energy expenditure, substrate oxidation or body composition in hypercholesterolemic males and females.<br /> (Copyright © 2012 Elsevier Inc. All rights reserved.)
- Subjects :
- Absorptiometry, Photon
Calorimetry, Indirect
Cross-Over Studies
Dietary Fats analysis
Fatty Acids, Monounsaturated chemistry
Female
Humans
Hypercholesterolemia pathology
Linseed Oil chemistry
Male
Oleic Acid analysis
Oxidation-Reduction
Rapeseed Oil
Single-Blind Method
Body Composition
Dietary Fats administration & dosage
Energy Metabolism
Fatty Acids, Monounsaturated administration & dosage
Hypercholesterolemia metabolism
Linseed Oil administration & dosage
Oleic Acid administration & dosage
Subjects
Details
- Language :
- English
- ISSN :
- 1532-8600
- Volume :
- 61
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Metabolism: clinical and experimental
- Publication Type :
- Academic Journal
- Accession number :
- 22698766
- Full Text :
- https://doi.org/10.1016/j.metabol.2012.04.016