The quest for self-identity: not all cancer stem cells are the same.

Authors :: Hjelmeland AB
Rich JN
Source :: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2012 Jul 01; Vol. 18 (13), pp. 3495-8. Date of Electronic Publication: 2012 Jun 18.
Publication Year :: 2012
Abstract: A central critique of the cancer stem cell (CSC) hypothesis involves the robustness of CSC markers. Zorniak and colleagues suggest that different progenitor marker profiles can classify CSCs, and improved modeling of cellular hierarchies can be achieved by incorporating inter- and intratumoral diversity.<br /> (©2012 AACR.)

Subjects :: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase
Animals
Humans
Biomarkers, Tumor metabolism
Brain Neoplasms enzymology
Gene Expression
Glioblastoma enzymology
Phosphoric Diester Hydrolases metabolism

Language :: English
ISSN :: 1557-3265
Volume :: 18
Issue :: 13
Database :: MEDLINE
Journal :: Clinical cancer research : an official journal of the American Association for Cancer Research
Publication Type :: Academic Journal
Accession number :: 22711710
Full Text :: https://doi.org/10.1158/1078-0432.CCR-12-1456