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Prevalence of depressive and other central nervous system symptoms in HIV-infected patients treated with HAART in Spain.
- Source :
-
Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) [J Int Assoc Physicians AIDS Care (Chic)] 2012 Sep-Oct; Vol. 11 (5), pp. 321-8. Date of Electronic Publication: 2012 Jun 19. - Publication Year :
- 2012
-
Abstract
- This study was conducted to assess the prevalence of depressive symptoms, sleep disturbances, and subjective cognitive complaints in patients with HIV receiving highly active antiretroviral therapy. Participants completed the "Center for Epidemiological Studies Depression Scale" (CES-D) and a questionnaire on sleep disturbances and subjective cognitive complaints. Mean age of the 799 participants was 43.7 years and 67% were men. Adjusted prevalence of CES-D was 35.4% (95% confidence interval [CI]: 32.0-38.7), with no significant differences between gender and age groups. Sleep disturbances were more prevalent in older versus younger participants (74.0% [95% CI: 70.4-77.7] versus 63.3% [95% CI: 56.8-69.8]). Cognitive complaints were more prevalent in women (52.3% [95% CI: 46.4-58.2]) when compared with men (48.2% [95% CI: 44.7-51.6]). Hepatitis C virus coinfection was a strong predictor of depressive symptoms. Male gender and detectable viral load were independent risk factors for sleep disturbance. A higher CES-D score was an independent risk factor for sleep disturbance and cognitive complaints.
- Subjects :
- Adult
Age Factors
Anti-HIV Agents therapeutic use
Antiretroviral Therapy, Highly Active
Coinfection epidemiology
Coinfection psychology
Dyssomnias virology
Female
HIV Infections psychology
Hepatitis C epidemiology
Hepatitis C psychology
Humans
Male
Middle Aged
Prevalence
Psychiatric Status Rating Scales
Risk Factors
Sex Factors
Spain epidemiology
Surveys and Questionnaires
Viral Load
Cognition Disorders epidemiology
Depression epidemiology
Dyssomnias epidemiology
HIV Infections drug therapy
HIV Infections epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1545-1097
- Volume :
- 11
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002)
- Publication Type :
- Academic Journal
- Accession number :
- 22713685
- Full Text :
- https://doi.org/10.1177/1545109712448217