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Hepatoid microcarcinoma of the pancreas: a case report and review of the literature.
- Source :
-
Chang Gung medical journal [Chang Gung Med J] 2012 May-Jun; Vol. 35 (3), pp. 285-91. - Publication Year :
- 2012
-
Abstract
- Hepatoid differentiation in pancreatic carcinoma is a rare phenomenon. It occurs either as a pure form or as a component with other subtypes. Herein, we report a 52-year-old man with an ampullary large cell neuroendocrine carcinoma presenting with obstructive jaundice for 2 months. A 0.5-cm nodule was found in the pancreatic head. Morphologically, the nodule was composed of exclusively hepatocytic tumor cells and sinusoids with dysplastic cytology and capsular invasion. The patient did not have a hepatic mass or ectopic normal liver tissue. This is the first reported case of ampullary large cell neuroendocrine carcinoma coinciding with a pancreatic hepatoid microcarcinoma. The clinicopathological features of pancreatic hepatoid carcinomas and their histogenesis are discussed.
Details
- Language :
- English
- ISSN :
- 2309-835X
- Volume :
- 35
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Chang Gung medical journal
- Publication Type :
- Academic Journal
- Accession number :
- 22735061
- Full Text :
- https://doi.org/10.4103/2319-4170.106142