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[The importance of medical genetics study for the early diagnosis of mucoviscidosis].
- Source :
-
Vrachebnoe delo [Vrach Delo] 1990 Apr (4), pp. 101-3. - Publication Year :
- 1990
-
Abstract
- The method of specific DNA amplification was used to study the polymorphism of the length of restriction fragment in the system CS-7 and KM-19 locus D7S23 in the family C. It is shown that cohesion of alleles A2 and B2 with mutation of mucoviscidosis and presence of a mucoviscidosis gene occurred in a healthy sibling. The family C, is prospective for prenatal diagnosis of mucoviscidosis by the method of specific DNA amplification in the system KM-19 restrictase Pst-1 and CS-7-Hinf-6-1.
Details
- Language :
- Russian
- ISSN :
- 0049-6804
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Vrachebnoe delo
- Publication Type :
- Academic Journal
- Accession number :
- 2275139