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Autologous hematopoietic progenitor cell transplantation for multiple myeloma through an outpatient program.
- Source :
-
Expert opinion on biological therapy [Expert Opin Biol Ther] 2012 Nov; Vol. 12 (11), pp. 1449-62. Date of Electronic Publication: 2012 Jul 13. - Publication Year :
- 2012
-
Abstract
- Introduction: There are considerable concerns regarding the appropriate use of health care resources to reduce costs and waiting lists associated with autologous hematopoietic progenitor cell transplantation (AHPCT). One of the strategies to reach this goal is outpatient-based (OpB) AHPCT.<br />Areas Covered: We reviewed all the reported experiences in this field and illustrated the various models of OpB AHPCT.<br />Expert Opinion: The role of high-dose melphalan (HDM) followed by AHPCT in the treatment of Multiple Myeloma (MM) continues to evolve in the novel agent era and the International Myeloma Working Group recommends that AHPCT should be offered at some point in the course of the treatment program for a medically fit patient. The relatively short neutropenia and the limited extra-marrow toxicity after HDM support the hypothesis that MM patients are the most suitable for outpatient transplant programs. Various models have shown that the procedure is feasible and safe and may highly contribute to shorten waiting lists and to considerably cut health costs, with an improvement of quality of life. Ideal candidates may be those who are asymptomatic and fully active, who have a full-time caregiver and who can reside within easy reach from the transplant center.
- Subjects :
- Ambulatory Care psychology
Clinical Trials as Topic methods
Hematopoietic Stem Cell Transplantation psychology
Humans
Multiple Myeloma diagnosis
Multiple Myeloma psychology
Outpatients psychology
Quality of Life psychology
Transplantation, Autologous methods
Ambulatory Care methods
Hematopoietic Stem Cell Transplantation methods
Multiple Myeloma therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1744-7682
- Volume :
- 12
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Expert opinion on biological therapy
- Publication Type :
- Academic Journal
- Accession number :
- 22788745
- Full Text :
- https://doi.org/10.1517/14712598.2012.707185